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No Single Healthy Diet Exists for Different Individuals, at Least in Mice

In No one-fits-all healthy diet exists, Science News reports:

Weight gain may depend on how an individual’s genes react to certain diets, a new study in mice suggests...

One strain, the A/J mouse, was nearly impervious to dietary changes. Those mice didn’t gain much weight or have changes in insulin or cholesterol no matter what they ate: a fat-and-carbohydrate-laden Western diet, traditional Mediterranean or Japanese diet (usually considered healthy) or very low-carbohydrate, fat-rich fare known as the ketogenic diet.

In contrast, NOD/ShiLtJ mice gained weight on all but the Japanese diet. Those mice’s blood sugar shot up — a hallmark of diabetes — on a Mediterranean diet, but decreased on the Japanese diet.

... “there’s no universally healthy diet,” Barrington said. The findings echo results of a human study in which blood sugar rose in some people after eating some foods, even when the same food had no effect on other people. Such individual reactions to food suggest that diets should be personalized.

WIND: humans love to tell each other which is the “best” diet, but what if that advice is nonsense or even quite long-term dangerous, for one person vs the other? What about the gut microbiome in combination with genes?

Insanity today: for an individual, the food pyramid, diet books, “healthy eating” and so rank right up there with BMI as junk science. It’s going to take a long time to sort all this out when responses are individual.

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