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How Artificial Sweeteners Destroy Your Gut Microbiome

re: microbiome
re: Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms
re: Typical American Diet Can Damage Immune System, Microbiome
re: excitotoxin

This summary discusses the issues with artificial sweeteners and the gut microbiome.

One of these, aspartame is also neurotoxic to the brain, being an excitotoxins.

The Epoch Times: How Artificial Sweeteners Destroy Your Gut

BY JOSEPH MERCOLA, July 24 2021.

Zero calories often means zero nutrition and a host of potential problems.

...Scientists have found that three of the most popular artificial sweeteners, including sucralose (Splenda), aspartame (NutraSweet, Equal, and Sugar Twin), and saccharin (Sweet’n Low, Necta Sweet, and Sweet Twin) have a pathogenic effect on two types of gut bacteria...

Just 2 Cans of Diet Soda Can Alter Beneficial Bacteria

The current molecular research from Angelia Ruskin University found that when E. coli and E. faecalis became pathogenic, they killed Caco-2 cells that line the wall of the intestines. Much of the past research demonstrating a change in gut bacteria had used sucralose.

However, data from this study showed that a concentration from two cans of diet soft drinks, using any of the three artificial sweeteners, could significantly increase the ability of E. coli and E. faecalis to adhere to the Caco-2 cells and increase the development of bacterial biofilms...

Artificial Sweeteners Can Sabotage Your Diet Goals

...It appears that the jump in adults using low-calorie sweeteners that occurred from 1999 to 2012 has remained steady through 2020. This may be due in part to the growing evidence that low-calorie sweeteners, such as Splenda, are a large contributor to the growing number of individuals who are overweight and obese...

Diet Drinks Increase the Risk of an Early Death

One 20-year, population-based study of 451,743 people from 10 European countries discovered there was also an association between artificially sweetened drinks and mortality....

More Health Damage Associated With Artificial Sweeteners

This same study also found a link between drinking soft drinks and Parkinson’s Disease “with positive nonsignificant associations found for sugar-sweetened and artificially sweetened soft drinks.”

Aspartame is another artificial sweetener that has been studied in the past decades. In one study, researchers asked healthy adults to consume a high-aspartame diet for eight days, followed by a two-week washout and then a low-aspartame diet for eight days.

During the high-aspartame period, individuals suffered from depression, headache, and poor mood. They performed worse on spatial orientation tests, which indicated aspartame had a significant effect on neurobehavioral health.

A second study evaluated whether people with diagnosed mood disorders were more vulnerable to the effects of aspartame. Researchers included 40 individuals with unipolar depression and those without any history of psychiatric disorder. The study was stopped after 13 completed the intervention because of the severity of the reactions.


WIND: excess sugar of any kind is a bad idea, but artificial sweeteners are even worse.

Correlation is not causation, so I’m not ready to sign up for the excess deaths or obesity things. But evidence is building and one of these studies suggest any benefits to artificial sweeteners.

I am ready to assert that the artificial sweetener aspartame, which turns into the neurotransmitter aspartic acid is causative for neurological disorders like Parkinson’s disease. An insidious excitotoxin, aspartame-induced brain-damage builds over time until there are no longer enough neurons to do their job, leaving its victims crippled. Those (like me) who have had concussion, or those infected with COVID are at hugely increased risk while the blood-brain barrier is only partially functional, letting excitotoxins wreak havoc.

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