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Antibiotics May Alter Infant Brain Development

re: ethics in medicine

Real science is never settled, and anyone who has certainty on such things is not qualified to discuss it.

When it’s life or death as with my daughter in the NICU years ago (sepsis, death imminent), you don’t worry about the side effects. But it should give pause to parents on multiple fronts.

The Epoch Times: Antibiotics May Alter Infant Brain Development: Study

byJennifer Margulis, 2021-10-19

A new study published in a special issue of the journal iScience links low doses of antibiotics around birth to significant changes in the infant microbiome. The study, conducted on mice, also linked antibiotic exposure to important changes in gene expression in parts of the brain responsible for neurodevelopment.

This research, “Effects of Early-Life Penicillin Exposure on the Gut Microbiome and Front Cortex and Amygdala Gene Expression,” may help explain the disturbing rise in neurodevelopmental disorders that we’re seeing in children in the United States and other industrialized countries around the world.

...

Low-Dose Penicillin Exposure Disrupts the Microbiome

The scientists found that exposure to even low doses of penicillin changed the composition of the microbiome in the mice... Most disturbingly, perhaps, this experiment showed that multiple pathways crucial for normal neurodevelopment were negatively affected in the antibiotic-exposed mice.

Because the doses of penicillin were so low, the researchers argued that it’s unlikely that the brain effects they observed were a direct result of the antibiotics themselves. Instead, they hypothesized that it’s more likely that the brain changes observed in the mice were due to the changes in their microbiomes.

In other words, due to antibiotic exposure, “the gut-brain axis is perturbed leading to organizational effects that permanently alter the structure and function of the brain,” according to the scientists.

...“These results provide evidence that early-life antibiotic exposure in humans may have effects not only on the infant microbiome but also on gene expression within critical brain structures, including the frontal cortex and amygdala, which are vulnerable to perinatal insults,” the scientists wrote.

..there’s evidence that a large percentage—perhaps as much as one-third—of the 3.75 million babies born in the United States each year are getting dosed with antibiotics before, during, or just after birth.

...But in recent years, peer-reviewed scientific research has linked antibiotic exposure to an increased risk of obesity, an increased risk of asthma, and higher incidents of bowel diseases and even juvenile arthritis.

...“We also know that the gut flora that’s developed in the first thousand days of life has a profound impact on the child’s chances of having chronic illness later in life,” Mumper said. “In general, the more diverse gut flora, the less the child is likely to have chronic illness later on, and antibiotics have the effect of killing off some of that good gut flora, therefore leading to less diversity.”

...

WIND: “safe and effective”? That’s the mantra of experts too arrogant to understand just how complex the bio-environment of human or animal really is. Yet over and over, we find that years or decades later things thought to be “settled science” are in fact woefully in error. New-technology mRNA vaccines anyone? They are safe and effective!

The frontal cortex and amygdala are crucial to self control, fear and anxiety, etc. Damaging those structures of very serious concern.

My bet is that numerous adult conditions are in fact the end result of damage from antibiotics, hormone look-alike chemicals, pollution, and the toxins of modern life. Many of which are in the food that 90% of the population eats 90% of the time.

Mice are not people, but all mammals prety much develop the same early on, at least from what I understand. This is one case where the results almost certainly apply to humans.

It is a RULE in medicine that if things don’t go awry right away in some obvious clinical way, it is then considered generally safe and effective.

Antibiotic use before or around the time of birth has long been considered to have minimal adverse effects on babies. However, studies that suggest they’re safe have only looked for the most obvious, short-term consequences of antibiotic over-use, such as increased thrush infections (an overgrowth of yeast usually kept in check by a healthy microbiome). These older studies haven’t examined longer-term health consequences.

... best practices included... vaccinating children on an evidence-based, but less aggressive vaccine schedule.

“Considered” means “guessing” which means “taught in medical schools as the gospel”. It is not science. Got your mRNA COVID vaccine yet? The child abusers in California and now the Dementia Patient in Chief wants to vaccinate children as young as five, masked-up of course. It is generally considered to have minimal adverse effects! And it’s very profitable. What’s not to like?

See also: Infections During Childhood Increase the Risk of Mental Disorders

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