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Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2

re: COVID

Nasty prospect, if I undertand what is being said. Let’s see if it is confirmed.

Anon MD writes:

They are seeing that mRNA produced spike proteins can translocate in to the nuclear DNA and make it easier to have an infection.

Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2

2022-09-25. Emphasis added.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe pathophysiology in vulnerable older populations and appears to be highly pathogenic and more transmissible than SARS-CoV or MERS-CoV [1, 2].

The spike (S) protein appears to be a major pathogenic factor that contributes to the unique pathogenesis of SARS-CoV-2. Although the S protein is a surface transmembrane type 1 glycoprotein, it has been predicted to be translocated into the nucleus due to the novel nuclear localization signal (NLS) “PRRARSV”, which is absent from the S protein of other coronaviruses. Indeed, S proteins translocate into the nucleus in SARS-CoV-2-infected cells. To our surprise, S mRNAs also translocate into the nucleus. S mRNA colocalizes with S protein, aiding the nuclear translocation of S mRNA. While nuclear translocation of nucleoprotein (N) has been shown in many coronaviruses, the nuclear translocation of both S mRNA and S protein reveals a novel pathogenic feature of SARS-CoV-2.

...

WIND: lots of research remains to be done on the numerous nasty effects of COVID and Long COVID, and the COVID Jabs. The biolab warfare people responsible for this scourge to humanity should all be prosecuted for crimes against humanity.

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