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Study: Cruel Aspartame and Anxiety Connection

re: excitotoxin
re: mental health

Aspartame is an excitotoxin and should be strictly avoided. Why would you ingest a substance that breaks down into a neutrotransmitter (eg excitotoxin), wood alcohol (methanol), and phenylalanine*?

The feckless FDA tells you that aspartame is safe. Big Food makes sure it stays that way.

Most studies are baloney. But this one seems particularly nasty in its findings.

* Aside from brain damage and intellectual disability and seizures for some people, don’t worry about it.

Study: Cruel Aspartame and Anxiety Connection

2023-01-15

If you are looking for yet one more reason to avoid consuming the artificial sweetener aspartame, the results of a new study may help. According to researchers at Florida State University College of Medicine, results of their four-year animal study showed an increased risk of anxiety associated with the use of aspartame. And there’s more: the increased risk was found to extend for up to two generations of the animals, as the trait was passed to both male and female offspring.

The Aspartame and Anxiety Study

In the study, which appeared in the December 2, 2022 issue of the Proceedings of the National Academy of Science, the researchers gave drinking water that contained aspartame to mice daily. The dose used was approximately 15 percent of what the Food and Drug Administration has determined to be the approved maximum daily for humans to consume. According to the FDA, the acceptable daily intake of aspartame for adults and children in the United States is 50 milligrams per kilogram (50 mg/kg) of body weight daily. Since 1 kilogram equals 2.2 pounds, a person weighing 110 pounds could safely consume 2,500 mg (or 2.5 gm) of aspartame daily, according to the FDA.

In this study, which lasted 12 weeks and was conducted over four years, the dosage was equal to six to eight 8-ounce cans of diet soda daily for humans. The length of the study allowed the researchers to track the impact of aspartame use over several generations of mice.

... The passage of anxiety to succeeding generations is an example of epigenetic (temporary) change. Unlike genetic changes (i.e., mutations), epigenetic changes do not alter DNA, but they do change how the body interprets DNA sequences...

... Once you consume aspartame, it transforms into aspartic acid, methanol, and phenylalanine. All of these metabolites can have significant effects on the function of the central nervous system. For example, the metabolites have an impact on the brain and neurotransmitter levels and have thus been associated with depression, headache, and convulsions.

Another example is methanol, which affects the liver. Methanol is oxidized in the liver to formaldehyde and then formic acid, both of which can damage liver cells. A recent report also noted that aspartame “could have carcinogenic properties” and that “exposure to aspartame from prenatal age increases the incidence of lymphomas/leukemias in females.”

...

WIND: read that again: “dose used was approximately 15 percent of what the Food and Drug Administration has determined to be the approved maximum daily for humans to consume”.

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