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Blood clotting may be the root cause of Long COVID syndrome, research shows

re: Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms
re: Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation
re: Long-Haul COVID

Real science is never settled, and anyone who has certainty on such things is not qualified to discuss it.

Makes some sense, but IMO there is a lot more going on, and this might be a red herring for many cases of Long-Haul COVID, or only one of many factors.

Science News: Blood clotting may be the root cause of Long COVID syndrome, research shows

2021-08-16

New evidence shows that patients with Long COVID syndrome continue to have higher measures of blood clotting, which may help explain their persistent symptoms, such as reduced physical fitness and fatigue.

New evidence shows that patients with Long COVID syndrome continue to have higher measures of blood clotting, which may help explain their persistent symptoms, such as reduced physical fitness and fatigue...

...researchers examined 50 patients with symptoms of Long COVID syndrome to better understand if abnormal blood clotting is involved... clotting markers were significantly elevated in the blood of patients with Long COVID syndrome compared with healthy controls. These clotting markers were higher in patients who required hospitalisation with their initial COVID-19 infection, but they also found that even those who were able to manage their illness at home still had persistently high clotting markers.

The researchers observed that higher clotting was directly related to other symptoms of Long COVID syndrome, such as reduced physical fitness and fatigue. Even though markers of inflammation had all returned to normal levels, this increased clotting potential was still present in Long COVID patients.

...

WIND: to suggest that clotting is a root cause based on such a small study is quite stretch, especially given this much more thorough analysis. And it just seems highly unlikely to have one root cause. But it cannot be ruled out as a factor.

What’s lacking here is how “clotting markers” relate to the clinical problems. I’d like to see some direct cause/effect shown.

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